Molecular
and Cellular Radiation Neuro-Oncology Laboratory |
| Associate
Professor of Radiation Oncology
Massachusetts General Hospital
Harvard Medical
School
Email:
achakravarti@partners.org |
| Members
of the Chakravarti Lab: |
Students: - Areej
El-Jawahri
- Vincent
Depalo
- Jenna
Kahn
- Angelika
Modelska
- Anshu
Shukla
- Zachary
Reardon
- Nikol
Mladkova
- Mike
Erkkinen (alumni)
- Greg
Saia (alumni)
- Erin
Tyndall (alumni)
|
|  | | The
Chakravarti
Laboratory 2008:
The
Laboratory of Molecular and Cellular Radiation Neuro-Oncology | | |
Lab
Contact Information:
Richard
B. Simches Research Center,
Brain Tumor Research Center,
Massachusetts
General Hospital
CPZN-3-3800
617-643-3427 (phone)
617-643-3229
(fax)
Email: achakravarti@partners.org
 | COMET
assay to
determine DNA damage
after irradiation. | |
Chakravarti,
A. ; Loeffler, J. S. ; Dyson, N..J. Insulin-like growth factor receptor I (IGFRI)
mediates resistance to anti-epidermal growth factor receptor (EGFR) therapy in
primary human glioblastoma cells through continued activation of phosphoinositide
3-kinase signaling. Cancer Res. 2002; 62(1):200-207.
Chakravarti, A.;
Noll, E.; Black, P.B.; Dyson, N.J.; Loeffler, J.S. Quantitatively-determined Survivin
expression levels are of prognostic value in human gliomas. J Clin Oncol. 2002;
20(4):1063-1068
Chakravarti, A.; Chakladar, A.; Delaney, M.A.; Latham,
D.E.; Loeffler, J.S. The epidermal growth factor receptor pathway mediates resistance
to sequential administration of radiation and chemotherapy in primary human glioblastoma
cells in a RAS-dependent manner. Cancer Res. 2002; 62(15):4307-4315 Chakravarti,
A.; Heydon, K.; Wu, C-L; Hammond, E.; Pollack, A.; Roach, M.; Wolkov, H.; Okunieff,
P; Komaki, R.; Fontanesi, J; Abrams, R.; Pilepich, M.; Shipley, W. Loss of p16
expression is of prognostic significance in locally advanced prostate cancer:
An analysis from RTOG 86-10. J Clin Oncol 2003; Chakravarti,
A.; Zhai, G.; Suzuki, Y.; Sarkesh, S.; Black, P.; Muzikansky, A. ; Loeffler, J.
The Prognostic Significance of Phosphatidylinositol 3-Kinase Pathway Activation
in Human Gliomas. J Clin Oncol 2004 May 15;22(10):1926-33. Zhang,
M., Chakravarti, A. Novel radiation-enhancing agents in malignant gliomas. Semin
Radiat Oncol. 2006 Jan;16(1):29-37. Chakravarti,
A.; Zhang, M.; Khor, L-Y.; Pollack, A.; Shipley, W. The prognostic value of p16
in locally-advanced prostate cancer: a report from RTOG 9202. J. Clin Oncol 2007;
25(21): 3082-3089.
Stupp, R., Hegi, M.; Gilbert, M.; Chakravarti, A.
Chemoradiotherapy in malignant glioma: standard of care and future directions.
J. Clin Oncol 2007; 25(26): 4127-4136.
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